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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b53daf7fc2a9d55d64b7b7bcd5c6377d994097b5a293fb62297179048a2d15f' 
  AND token = 'gwTg5MFuIYKoDqF6IIfmLtyssQuVMX4nBWLCMB7hLdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}