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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdb0a0fb84f840ce290ab36dc5ab29f92848f36c0e8f142f3d992eb3d33fc44a' 
  AND token = '+mzmewdEsYaX4d8TqbRPquk6TK/NaL+PKRUUgaEjC1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}