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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78f557cff3be7e2c2b600caf1bb8526a3e9006730912045e554d69ce0d951e10' 
  AND token = 'lYyejUFXWG9085XbldT1rQQCOYSTcR/vDB7V3T1QHXA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}