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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f22aa54bdc51680063b57cdb9be0ba82757e0387c0e60ddec0943812c9d8ac44' 
  AND token = 'L7sVidhidwzvE+cepARwX5uk+1ouK4ipkOm+OY0ZfrM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}