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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1cf001cfb5f285ef4bada0ad1f8a89894e845abbefd891502dccbc5275e76b3' 
  AND token = 'CDHWkdDFZ+baltx3wjqlZzfxsCimdlJUJxp//BjSn7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}