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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf508285abe7a26d084d502e66d3ac53c3a68a6c16237714b5fb409d5284c45' 
  AND token = 'JJLOgfxmbjoZsQ7H8W/nHytpyhAo8T8zdazcBlbO260=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}