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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '143eaa0b73b0dae44b65175d85ce6f89ca09fdf4a2da944bc6abf791e62e5177' 
  AND token = 'FJUAidR4d1axDCkEgoTolqUrV9OsZB1jww4VJSzqgNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}