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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e340f43e99ee24523a6754420a5984459afe6e20e451ebf11d04e6d65052f84' 
  AND token = 'nkXg0GEONhRzb/KSRsM0UTUjgmmF60uWVOc2XYIJAKQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}