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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980a82d906695b71bc560d1bd90435c1d35209add30c9c6a3dc825a6b9ee24c1' 
  AND token = 'GfLJq8R+HtmO1kkSAwRRhjO7K3/pZXTyui1t65Ewajg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}