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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd2916f79b1b8b22586b7d8dd1d120158e6e439970fcaa990f91675f7dca99c1' 
  AND token = 'aoqJ2P3EFY7swzOK9DaZ7fW0iih5zj6okBYfDhNPJpI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}