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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '433fc85d5d354d2b1dff854ddbb2e763d77324dc73ff444ea0091f85b3d7dfd2' 
  AND token = '7x7eQ9K9b+uvgeKSMFIAAYb3CEAuz8piqfSJzOr/Ifc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}