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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c819e3dbbe12b81d2d9d8006101065d53cb3f5dda6d5fcaacc2225b5cd871229' 
  AND token = 'sSX7VK12gLCc0Cdx/fHnfhV3Y5LUlOGWelY818fubdA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}