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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3da1c59c709a5f29c60620f621b707b2d20b3b87e56af2872dad88da75a48185' 
  AND token = 'hf1/gSm4HdrxddtDTViHONhaHva7o49n+8aAJt8VPNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}