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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '668257fa3ec0cbe77d91b547c3b4faa4daacaf958f596472be2568a7a4873e90' 
  AND token = 'yuCDyQ4s0tcxVP+Cd9cBVntObeEwlWqx/Uf4Km6Irqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}