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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6ae4351de8180927545bb4954c13d257691d95b7524ba844e25e4c4ec34486' 
  AND token = 'eL7r5rcPEKUESOIfeFaS/dsG490tJtbOrS1mIBo4TTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}