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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b9fe217b7dc76dbbe5d6725a56a7a35f7c9e33624368e46393a4b5f4b3b74172' 
  AND token = 'EXp51CfyREtnRHC6sklCg/3ILyynBQyTdw5u4GYkX34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}