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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7e8f427cedb8f2fe06262adac6e7a9d4998f02d745e304a02fa755934d8122a' 
  AND token = 'uu+rrMY/whupm0Nd5cxHssIRpwrl6mmkWH5CQR6kjGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}