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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6396f2f94bb8d5c288aafa34f7a52b4b3b67f640cd476b9e0d934ec9f276642' 
  AND token = 'm4PrpzUiuTI049MHxnGyYJDY0Pv2/dEMa9Tj9Kp5ltg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}