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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4178760e72f42500e2088bc9d5d9242307030dca81b10e4f3c08393b94a5b26' 
  AND token = 'zn2a3MXGPtL1CqQnmA3h8HhP2PFXzbcNdDQRtQapAi0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}