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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a580d79d08e18b5abf51a98a2160379f3dc9d3e808fc6ead6208c4c223d7cc4' 
  AND token = 'wqhuXo7Zw6Mzq06sIxPnhCcYN194hLQbTTi6uMlF7zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}