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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e51b0517ec3700510e5ccc87a806701ad276364e4d7627e6da14485808fb03f' 
  AND token = '+lwo/ei0vNBRhjcYdYSPFYHZV/SalPJAOxM5D33bw28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}