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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1adbe17285d266f81759d222858c56c3ea7451c2ee455321f0b8e438146e07d9' 
  AND token = 'Iv8Hht9tZtewsK70Qfj/yHR4opU6ejml2dkSjZ0H500=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}