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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cdeb8f33a6b04dc98199eb0f05b3672ea103775ba6cf844e473a2465939a0118' 
  AND token = 'z4mzvhV/+rfiWiRcK+4XrF4hd5yQhUWhiNqa1vz1CN4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}