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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46f4f1c181761c95a3579dfe1d0910444f7f723f74427c1bbdbf108ff3a4fa61' 
  AND token = 'uTPc5nNSYCVGqHDmGm4zwbeO6WH4VE1pG4Nz9TBsxKo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}