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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8c9df943aa1d7faa6045de27229c0df012c33394295e60289653572a5d49f2' 
  AND token = 'VgAITjMy4KQSu9nHyTGBPF3u/CyjqTNdy2kD8207LAc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}