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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb0eefca49fdc389d34df24ee66a0943aaa8fba2faa36b66d4cac1343c58b160' 
  AND token = 'xSl/nEnlYNPKRMC32AHc2iWX5WGkcDd8DJgVr2Kz2ss=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}