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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2b5e06e96085ad40c77ec2f0cf96d5ccd02b6be3d07e8d6717c6519c582340' 
  AND token = 'JQuycSZqtqp3+lQ11Xnt2XCz2Oz9Na5Yu5u0AKY6lXw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}