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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61f6aa45cdea96df678154a487e7b94d621753b7fa84c5de825b50d8d0fbb458' 
  AND token = '3vuLhbOdEFUFhHBWiICoeMHb75zSNlYkC96goN8rtQk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}