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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5b0977f36e8379adecf46a9564e184ed504cca75ad86b13f9fb7e1fae601ed4' 
  AND token = 'Ok/Y13lfCrLOevdfqq31bmdlCIN3r1gQtmVJL5IN8Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}