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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25121a98d5e2154b4f167014a6364ca35759bd3a64d61151bddee94e9c225aa6' 
  AND token = 'hBVTosNeO54MZKymPOAPGlGy3pMiEN9nMwpwKLQ5A4E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}