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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd197aa3ec6f2d28d79c7c7d050d4689d2c03fbf3a1ee85c3329584814231b482' 
  AND token = 'asaeN4mQSo8W+dQwAVmCBNTDhxKVWLn3X1PC/NqdfsE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}