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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be3451e39d26312c87035934ac60657c9a9e1828c6faa42e9492b6c954b49163' 
  AND token = 'bYOAjsogdXzVj+Ke9LMvaXkdMU0hCen0J3QUN5+KUMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}