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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '485789c5679daf1a6de3d5c2b9b8b8eb1ba0a91bde05609c02ed4f6dd1ca450a' 
  AND token = 'NtwK5rL6LkFs+SArvHt2JUSCM5d7NEs71uqVXM30Kfk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}