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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2180fbabd3057599ae838fdc3c40f14f8f2a92a5c898cd0b5ada36a82d2839da' 
  AND token = '18xCblnrCUnTk6zdnm/D04Y0neRwHrHxHaX7DYm55IM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}