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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80f00cce8cd33df89be613b154ba9f546ca61e5344f7d340c4ee4c1e53d2922b' 
  AND token = 'UqB5Vf5HE4rw0gxFO3KPyUWg3uzEYXnh1R67uPxki8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}