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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '565d3e24f9b501c0b8278130e0503e0054dd9e408017757c9c50df4bb8e10e0f' 
  AND token = 'pj8BD5RMeUSSFIo0ZdfTr65L8KMDmW81HXXL/pN4KXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}