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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37ff31c3fe4dd557edb9724913f9b876e526185dcefea10ef00833d394d6fe6e' 
  AND token = 'mP15U8EanWdZeAYzu5nP96+UQQsujgopxxZDnHGgd9Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}