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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2775b55d4f0ea4d86ea40843c42a633e44e300b0da5453e7cea6922e335bd5d8' 
  AND token = '9P1kmX14yh4GPliJo77TIc73+akfZb1vvBT7cLN7aO4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}