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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9af3df35b2dcb28760e1b2888b96306d224e09237b8cadc2d8e46e30ca54b6d' 
  AND token = 'u2gjLeK4tr2+pn8kb3AAFAEYiMYrt2k0IKOZiJ429k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}