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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '246b5711d9e301c8cff19a40e9aa35cfe4e2acb8a7f3992b732deaa027ee7d90' 
  AND token = 'yHSHqxsYwkS8DtkRk7CCf/Xp7H69gTj3DnhOiZLxczA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}