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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '214a02015e16721936c4298d405411a86ac31375aa9b7e1553c47b5a32a50d9e' 
  AND token = 'W2mJzEn12FjvLfIwboqg6xQ0rWTnvj4lMVTmUT9tyog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}