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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c87f8bbb9bb6b061ba9cd8fd68598256dece55307c076210413200d5fe8f81a' 
  AND token = 'EWv+eVCaM+Km7P6YV5ry7LAHCO4otGtQ4aWfREgQVQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}