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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ec928465ac967f0ee8a608fa00c6b4b773c0c186adcacb3b410a65413eea0a6' 
  AND token = 'Xqe6jtMEa0HFtHTU67U5iQxxCW/eJruzkrZ0M3QPWhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}