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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c37321811271ddb702bca9dbcbbb79d5c579213fdcebacc98be21541b1645c96' 
  AND token = 's7o70Yl0uKve+k8HrvzLxUf169YaOGmvsxm99hBroHw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}