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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37f8cfd5cdf7551f2dbd9f7230ea1841231bc4b7b3a0c034adee40dd148f2277' 
  AND token = '/qSy+WH3PiK/A9z90Tf4IkDbgBWoPlxGDlmmcetQ/qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}