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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '08604ffdfc9b737803bb5dc40d2c615f0d27bc97cca35fa92265008010bf3460' 
  AND token = 'ahu5OkWIPf0Jc02pj/i8Au1lZhw1Epxl+4KO2hcFiKY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}