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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72d8a6e78781601d06e7cc0e01f1ef9e8b560d6a1a7c6b5bbc90f7b25edef22c' 
  AND token = 'Miithe2V7c3XKe7S1pNHl9uLx9B7zCDxfmvX5Mi5zTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}