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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4a8440881e076e3b4b30b65b48eb5460c325e49b9ae05c3b8655b6d1abf554d' 
  AND token = 'ezaSJyyUxhEUX8CUmp7byKAJx+h7rvg2pGWx8Db7EBs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}