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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b0dd650ee0e1a035b7e64c1dc1f81bc67ef146ce36df7c7010e64e5113cb028' 
  AND token = 'Ex6wYTST6XxntE+8Jp6gIaoHvZZipMoImrc9SNXi264=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}