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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '305d40cb227ac6f3dbb8e1f65b67cd45597ff7d282d46fdecab80416932fd3fb' 
  AND token = 'SGD0IhipUpQZXsoe/cst8TZx/BJLfrNUjC0EMEFhgfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}